Phosphodiesterase Isozymes Involved in Regulation of HCO 3-Secretion in Isolated Mouse Stomach In Vitro

@inproceedings{Kita2008PhosphodiesteraseII,
  title={Phosphodiesterase Isozymes Involved in Regulation of HCO 3-Secretion in Isolated Mouse Stomach In Vitro},
  author={Kazutomo Kita and Kento Takahashi and Yumi Ohashi and Hironori Takasuka and Eitaro Aihara and Koji Takeuchi},
  year={2008}
}
( )-(E)-4-Ethyl-2-[(E)-hydroxyimino]-5-nitro-3-hexenamide] (NOR-3), a nitric-oxide (NO) donor, is known to increase HCO3 secretion in rat stomachs, intracellularly mediated by cGMP; yet, there is no information about the phosphodiesterase (PDE) isozyme involved in this process. We examined the effects of various isozyme-selective PDE inhibitors on the… CONTINUE READING