Phosphodiesterase 5 inhibitors in the treatment of premature ejaculation.

  title={Phosphodiesterase 5 inhibitors in the treatment of premature ejaculation.},
  author={Wei-fu Wang and Suks S Minhas and David John Ralph},
  journal={International journal of andrology},
  volume={29 5},
To date, there is no FDA-approved therapy for premature ejaculation (PE). Recently, phosphodiesterase 5 inhibitors (PDE5-Is) have been demonstrated to have encouraging results in the treatment of PE by a few studies. The aim of this review was to assess the updated manuscripts and thereafter present the practical recommendations and possible mechanisms concerning PDE5-Is for treating PE. Using MEDLINE, we searched and assessed the peer manuscripts published from 1 January 1996 to 1 September… CONTINUE READING


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