Phosphaturic action of fibroblast growth factor 23 in Npt2 null mice.


In the present study, we evaluated the roles of type II and type III sodium-dependent P(i) cotransporters in fibroblast growth factor 23 (FGF23) activity by administering a vector encoding FGF23 with the R179Q mutation (FGF23M) to wild-type (WT) mice, Npt2a knockout (KO) mice, Npt2c KO mice, and Npt2a(-/-)Npt2c(-/-) mice (DKO mice). In Npt2a KO mice, FGF23M… (More)
DOI: 10.1152/ajprenal.00375.2009


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@article{Tomoe2010PhosphaturicAO, title={Phosphaturic action of fibroblast growth factor 23 in Npt2 null mice.}, author={Yuka Tomoe and Hiroko Segawa and Kazuyo Shiozawa and Ichiro Kaneko and Rieko Tominaga and Etsuyo Hanabusa and Fumito Aranami and Junya Furutani and Shoji Kuwahara and Sawako Tatsumi and Mitsutu Matsumoto and Mikiko Ito and K. Miyamoto}, journal={American journal of physiology. Renal physiology}, year={2010}, volume={298 6}, pages={F1341-50} }