Phosphatidylinositol promotes cholesterol transport and excretion.

@article{Burgess2003PhosphatidylinositolPC,
  title={Phosphatidylinositol promotes cholesterol transport and excretion.},
  author={Jonah Burgess and Jonathan Boucher and Tracey A-M Neville and Patricia Rouillard and Chris Stamler and Susha Zachariah and Daniel L. Sparks},
  journal={Journal of lipid research},
  year={2003},
  volume={44 7},
  pages={
          1355-63
        }
}
Administration of phosphatidylinositol (PI) to New Zealand White rabbits increases HDL negative charge and stimulates reverse cholesterol transport. Intravenously administered PI (10 mg/kg) associated almost exclusively with the HDL fraction in rabbits. PI promoted an increase in the hepatic uptake of plasma free cholesterol (FC) and a 21-fold increase in the biliary secretion of plasma-derived cholesterol. PI also increased cholesterol excretion into the feces by 2.5-fold. PI directly affects… CONTINUE READING

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