Phosphatidylinositol 3-kinase: a molecule mediating BDNF-dependent spatial memory formation

@article{Mizuno2003Phosphatidylinositol3A,
  title={Phosphatidylinositol 3-kinase: a molecule mediating BDNF-dependent spatial memory formation},
  author={Makoto Mizuno and Kazuyuki Yamada and Nobuyuki Takei and Manh Hung Tran and Jia Cai He and Akira Nakajima and Hiroyuki Nawa and Toshitaka Nabeshima},
  journal={Molecular Psychiatry},
  year={2003},
  volume={8},
  pages={217-224}
}
  • Makoto Mizuno, Kazuyuki Yamada, +5 authors Toshitaka Nabeshima
  • Published 2003
  • Psychology, Medicine
  • Molecular Psychiatry
  • Brain-derived neurotrophic factor (BDNF) plays a critical role in synaptic plasticity such as long-term potentiation (LTP), a form of synaptic correlate of learning and memory. BDNF is also implicated in learning and memory. We have demonstrated that radial arm maze training in rats for spatial learning and memory results in a significant increase in the BDNF mRNA expression in the hippocampus. Moreover, antisense BDNF oligonucleotide treatment impaired not only acquisition, but also… CONTINUE READING

    Citations

    Publications citing this paper.
    SHOWING 1-10 OF 121 CITATIONS, ESTIMATED 60% COVERAGE

    Brain-Derived Neurotrophic Factor-Induced Gene Expression Reveals Novel Actions of VGF in Hippocampal Synaptic Plasticity

    VIEW 6 EXCERPTS
    CITES BACKGROUND
    HIGHLY INFLUENCED

    FILTER CITATIONS BY YEAR

    1978
    2020

    CITATION STATISTICS

    • 4 Highly Influenced Citations

    References

    Publications referenced by this paper.
    SHOWING 1-10 OF 29 REFERENCES