Phosphatidylethanolamine recognition promotes enteropathogenic E. coli and enterohemorrhagic E. coli host cell attachment.

@article{Foster1999PhosphatidylethanolamineRP,
  title={Phosphatidylethanolamine recognition promotes enteropathogenic E. coli and enterohemorrhagic E. coli host cell attachment.},
  author={Debora E Barnett Foster and Dana Philpott and Maan Abul-Milh and Mario Huesca and Philip M. Sherman and Clifford Lingwood},
  journal={Microbial pathogenesis},
  year={1999},
  volume={27 5},
  pages={289-301}
}
Using both solid phase and liposome aggregation assays, we screened a variety of glycolipids and phospholipids and found that EHEC and EPEC bind specifically and in a dose-dependent manner to PE. This binding was consistently observed whether the lipid was immobilized on a thin layer chromatography plate, in a microtitre well or incorporated into a unilamellar vesicle suspended in aqueous solution. There was no evidence of binding to other phospholipids such as phosphatidylcholine (PC) or… CONTINUE READING
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