Phosphatidylethanolamine in Trypanosoma brucei is organized in two separate pools and is synthesized exclusively by the Kennedy pathway.

@article{Signorell2008PhosphatidylethanolamineIT,
  title={Phosphatidylethanolamine in Trypanosoma brucei is organized in two separate pools and is synthesized exclusively by the Kennedy pathway.},
  author={Aita Signorell and Monika Rauch and Jennifer Jelk and Michael A. J. Ferguson and Peter B{\"u}tikofer},
  journal={The Journal of biological chemistry},
  year={2008},
  volume={283 35},
  pages={23636-44}
}
Phosphatidylethanolamine is a major phospholipid class of all eukaryotic cells. It can be synthesized via the CDP-ethanolamine branch of the Kennedy pathway, by decarboxylation of phosphatidylserine, or by base exchange with phosphatidylserine. The contributions of these pathways to total phosphatidylethanolamine synthesis have remained unclear. Although Trypanosoma brucei, the causative agent of human and animal trypanosomiasis, has served as a model organism to elucidate the entire reaction… CONTINUE READING
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