Phosphatidylethanolamine from Phosphatidylserine Decarboxylase2 is Essential for Autophagy Under Cadmium Stress in Saccharomyces cerevisiae

@article{Muthukumar2013PhosphatidylethanolamineFP,
  title={Phosphatidylethanolamine from Phosphatidylserine Decarboxylase2 is Essential for Autophagy Under Cadmium Stress in Saccharomyces cerevisiae},
  author={K. Muthukumar and V. Nachiappan},
  journal={Cell Biochemistry and Biophysics},
  year={2013},
  volume={67},
  pages={1353-1363}
}
  • K. Muthukumar, V. Nachiappan
  • Published 2013
  • Biology, Medicine
  • Cell Biochemistry and Biophysics
  • Cadmium (Cd) is a potent toxic element used in several industries and in the process contaminates air, soil, and water. Exposure of Saccharomyces cerevisiae to Cd increases the major phospholipids, and profound increase was observed in phosphatidylethanolamine (PE). In yeast, there are four different pathways contributing to the biosynthesis of PE, and contribution to PE pool through phosphatidylserine decarboxylase2 (psd2) is not significant in normal conditions. Upon Cd exposure, psd2Δ strain… CONTINUE READING
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    References

    SHOWING 1-10 OF 58 REFERENCES
    Endoplasmic reticulum is a major target of cadmium toxicity in yeast
    • 90
    Glutathione peroxidase3 of Saccharomyces cerevisiae protects phospholipids during cadmium-induced oxidative stress
    • 30
    Identification of a Non-mitochondrial Phosphatidylserine Decarboxylase Activity (PSD2) in the Yeast Saccharomyces cerevisiae(*)
    • 226
    • PDF
    Cadmium-induced oxidative stress in Saccharomyces cerevisiae.
    • 34
    • PDF
    Cadmium induces a heterogeneous and caspase-dependent apoptotic response in Saccharomyces cerevisiae
    • 45