Phosphatidylcholine supplementation in pregnant women consuming moderate-choline diets does not enhance infant cognitive function: a randomized, double-blind, placebo-controlled trial.

@article{Cheatham2012PhosphatidylcholineSI,
  title={Phosphatidylcholine supplementation in pregnant women consuming moderate-choline diets does not enhance infant cognitive function: a randomized, double-blind, placebo-controlled trial.},
  author={Carol L Cheatham and Barbara Davis Goldman and Leslie M Fischer and Kerry-Ann da Costa and J. Steven Reznick and Steven H Zeisel},
  journal={The American journal of clinical nutrition},
  year={2012},
  volume={96 6},
  pages={1465-72}
}
BACKGROUND Choline is essential for fetal brain development, and it is not known whether a typical American diet contains enough choline to ensure optimal brain development. OBJECTIVE The study was undertaken to determine whether supplementing pregnant women with phosphatidylcholine (the main dietary source of choline) improves the cognitive abilities of their offspring. DESIGN In a double-blind, randomized controlled trial, 140 pregnant women were randomly assigned to receive supplemental… CONTINUE READING
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Common genetic polymorphisms affect the human requirement for the nutrient choline.

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