Phosphatidylcholine prevents postoperative peritoneal adhesions: an experimental study in the rat.

@article{Arrajab1991PhosphatidylcholinePP,
  title={Phosphatidylcholine prevents postoperative peritoneal adhesions: an experimental study in the rat.},
  author={A Ar'rajab and Bo Ahr{\'e}n and Jacek Rozga and Stig Bengmark},
  journal={The Journal of surgical research},
  year={1991},
  volume={50 3},
  pages={212-5}
}
Phosphatidylcholine (PC) is the main constituent of the surface-active material coating peritoneal mesothelium. It may prevent postoperative adhesion formation through production of a lubricant film on mesothelial defects. We therefore examined the effect of its soluble form on surgically induced intraabdominal adhesions in rats. The adhesions were induced at laparotomy by any of four different operative models. PC was administered intraperitoneally (20 mg/rat) or intravenously (20 mg/rat or 50… CONTINUE READING