Phosphatidylcholine participates in the interaction between macrophages and lymphocytes.

  title={Phosphatidylcholine participates in the interaction between macrophages and lymphocytes.},
  author={A. Nishiyama-Naruke and R. A. Curi},
  journal={American journal of physiology. Cell physiology},
  volume={278 3},
The role of phosphatidylcholine molecules as mediator for the control of lymphocyte proliferation by macrophages was investigated. Phosphatidylcholine added to the culture medium inhibited the concanavalin A-stimulated lymphocyte proliferation in a concentration-dependent manner. The potency of this effect was dependent on the presence of arachidonic acid in the phosphatidylcholine molecules. The phosphatidylcholine transfer from macrophages to lymphocytes was then investigated. Macrophages… CONTINUE READING
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Evidence for the transfer in culture of [14c]-labelled fatty acids from macrophages to lymphocytes

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