Phosphate uptake by superficial and deep nephron brush border membranes

  title={Phosphate uptake by superficial and deep nephron brush border membranes},
  author={Mich{\`e}le G. Brunette and Meanthan Chan and Urs Maag and Richard B{\'e}liveau},
  journal={Pfl{\"u}gers Archiv},
Dietary phosphate restriction and acute parathyroidectomy in rat are known to be associated with a selective increase in phosphate uptake by renal cortical brush border membranes (BBM). Conversely, phosphate loading and parathyroid hormone (PTH) administration result in a decrease of this uptake. In the present study, we investigated whether the response of the membrane to these various stimuli implies similar or different modifications of the kinetic properties of this membrane, whether these… CONTINUE READING


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