Phosphate transporters in renal, gastrointestinal, and other tissues.

@article{Forster2011PhosphateTI,
  title={Phosphate transporters in renal, gastrointestinal, and other tissues.},
  author={Ian Cameron Forster and Nati Hernando and V{\'i}ctor Sorribas and Andreas Werner},
  journal={Advances in chronic kidney disease},
  year={2011},
  volume={18 2},
  pages={63-76}
}
Inorganic phosphate (Pi) is essential for all living organisms. Bound to organic molecules, Pi fulfills structural, metabolic, and signaling tasks. Therefore, cell growth and maintenance depends on efficient transport of Pi across cellular membranes into the intracellular space. Uptake of Pi requires energy because the substrate is transported against its electrochemical gradient. Till recently, 2 major families of physiologically relevant Pi-specific transporters have been identified: the… CONTINUE READING

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