Phosphate control over nitrogen metabolism in Streptomyces coelicolor: direct and indirect negative control of glnR, glnA, glnII and amtB expression by the response regulator PhoP

Abstract

Bacterial growth requires equilibrated concentration of C, N and P sources. This work shows a phosphate control over the nitrogen metabolism in the model actinomycete Streptomyces coelicolor. Phosphate control of metabolism in Streptomyces is exerted by the two component system PhoR-PhoP. The response regulator PhoP binds to well-known PHO boxes composed of… (More)
DOI: 10.1093/nar/gkp162

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@inproceedings{RodrguezGarca2009PhosphateCO, title={Phosphate control over nitrogen metabolism in Streptomyces coelicolor: direct and indirect negative control of glnR, glnA, glnII and amtB expression by the response regulator PhoP}, author={Antonio Rodr{\'i}guez-Garc{\'i}a and Alberto Sola-Landa and Kristian Apel and Fernando Santos-Beneit and Juan Francisco Mart{\'i}n}, booktitle={Nucleic acids research}, year={2009} }