Phosphatase and tensin homologue: a therapeutic target for SMA

Abstract

Spinal muscular atrophy (SMA) is one of the most common juvenile neurodegenerative diseases, which can be associated with child mortality. SMA is caused by a mutation of ubiquitously expressed gene, Survival Motor Neuron1 (SMN1), leading to reduced SMN protein and the motor neuron death. The disease is incurable and the only therapeutic strategy to follow… (More)
DOI: 10.1038/sigtrans.2017.38

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Cite this paper

@inproceedings{Godena2017PhosphataseAT, title={Phosphatase and tensin homologue: a therapeutic target for SMA}, author={Vinay K. Godena and Ke Ning}, booktitle={Signal Transduction and Targeted Therapy}, year={2017} }