Phosgene Exposure: Mechanisms of Injury and Treatment Strategies

@article{Borak2001PhosgeneEM,
  title={Phosgene Exposure: Mechanisms of Injury and Treatment Strategies},
  author={Jonathan Borak and Werner F. Diller},
  journal={Journal of Occupational and Environmental Medicine},
  year={2001},
  volume={43},
  pages={110-119}
}
  • J. Borak, W. Diller
  • Published 2001
  • Medicine
  • Journal of Occupational and Environmental Medicine
Phosgene (carbonyl chloride, CAS 75–44–5) is a highly reactive gas of historical interest and current industrial importance. Phosgene has also proved to be a useful model for the study of those biochemical mechanisms that lead to permeability-type pulmonary edema (adult respiratory distress syndrome). In turn, the study of phosgene-induced adult respiratory distress syndrome has provided insights leading to revised treatment strategies for exposure victims. We summarized recent findings on the… Expand
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CHAPTER 23 – Phosgene
Publisher Summary Phosgene is a colorless gas at ambient temperature and pressure, and inhalation is the most important route of exposure for phosgene. Phosgene is manufactured from a reaction ofExpand
Chapter 25 – Phosgene
Inhalation is the most important route of exposure for phosgene. A latency period occurs before phosgene affects the target organ, the lungs. The odor threshold is between 0.5 and 1.5 ppm, and theExpand
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