Phosducin regulates transmission at the photoreceptor-to-ON-bipolar cell synapse.

@article{Herrmann2010PhosducinRT,
  title={Phosducin regulates transmission at the photoreceptor-to-ON-bipolar cell synapse.},
  author={Rolf Herrmann and Ekaterina S Lobanova and Timothy Hammond and Christopher Kessler and Marie E Burns and Laura Frishman and Vadim Y Arshavsky},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={2010},
  volume={30 9},
  pages={3239-53}
}
The rate of synaptic transmission between photoreceptors and bipolar cells has been long known to depend on conditions of ambient illumination. However, the molecular mechanisms that mediate and regulate transmission at this ribbon synapse are poorly understood. We conducted electroretinographic recordings from dark- and light-adapted mice lacking the abundant photoreceptor-specific protein phosducin and found that the ON-bipolar cell responses in these animals have a reduced light sensitivity… CONTINUE READING
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