Phorbol myristate acetate stimulates pinocytosis and membrane spreading in mouse peritoneal macrophages

@article{PhaireWashington1980PhorbolMA,
  title={Phorbol myristate acetate stimulates pinocytosis and membrane spreading in mouse peritoneal macrophages},
  author={L Phaire-Washington and Eric Shing-Suan Wang and Samuel C. Silverstein},
  journal={The Journal of Cell Biology},
  year={1980},
  volume={86},
  pages={634 - 640}
}
Phorbol myristate acetate (PMA) at a concentration of 0.01 microgram/ml causes an approximately threefold increase in surface area of resident, proteose-peptone-elicited, and thioglycolate-broth-elicited mouse peritoneal macrophages. Resident and proteose-peptone-elicited macrophages, cultured for 24 h in the presence of PMA, increase their pinocytic rate twofold in response to addition of PMA (0.01 microgram/ml) to the medium. Thioglycolate-broth-elicited macrophages, cultured for 24 h in the… CONTINUE READING

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