Phorbol myristate acetate and calcium ionophore A23187 modulate the accessory cell function of mouse dendritic cells.

Abstract

Dendritic cells (DC) comprise a small subpopulation of lymphoid cells, with distinct morphologic features, surface phenotypes and a potent accessory function in T cell-dependent immune responses. In the present study, we investigated the in vitro effects of a tumor promoter, phorbol myristate acetate (PMA), and calcium ionophore A23187 on the accessory cell… (More)

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