Phorbol ester treatment inhibits proliferation and differentiation of cultured human skeletal muscle satellite cells by differentially acting on protein kinase C isoforms

Abstract

We have previously shown that cultured human skeletal muscle cells express five protein kinase C (PKC) isoforms (PKCα, -γ, -η, -θ, and -ζ) and that expression levels of various PKC isozymes differentially change during differentiation. In this study we investigated the effects of the PKC activator phorbol 12-myristate 13-acetate (PMA) on differentiation and… (More)
DOI: 10.1007/s004010000347

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