Phorbol ester-induced contraction in chemically skinned vascular smooth muscle.

@article{Chatterjee1986PhorbolEC,
  title={Phorbol ester-induced contraction in chemically skinned vascular smooth muscle.},
  author={Madhumita Chatterjee and Manuel Tejada},
  journal={The American journal of physiology},
  year={1986},
  volume={251 3 Pt 1},
  pages={C356-61}
}
We studied the contractile response to phorbol esters and its relationship to myosin light chain phosphorylation in intact and Triton X-100-skinned porcine carotid preparations. Muscle contraction was activated by phorbol 12,13-dibutyrate (PDBu) and phorbol 12,13-didecanoate (PDD). Dose-dependent contractions to PDBu were obtained both in the intact and… CONTINUE READING