Phorbol ester-induced G2 delay in HeLa cells analyzed by time lapse photography.

@article{Kinzel1988PhorbolEG,
  title={Phorbol ester-induced G2 delay in HeLa cells analyzed by time lapse photography.},
  author={Volker Kinzel and G Bonheim and Juli{\'a}n Richards},
  journal={Cancer research},
  year={1988},
  volume={48 7},
  pages={
          1759-62
        }
}
The tumor promoter 12-O-tetradecanoylphorbol-13-acetate (TPA) has been shown previously to mimic X-irradiation in altering cell cycle parameters in Hela cells [Kinzel, V., Richards, J., and Stöhr, M., Science (Wash. DC), 210: 429-431, 1980]. These changes include a delay in G2 phase from which cells recover in the presence of TPA, which suggests an involvement of cellular mediators. In order to obtain information on the onset and the duration of the G2 delay, as well as the onset and rate of… CONTINUE READING

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SHOWING 1-10 OF 27 REFERENCES

Induction of chromosomal alterations in primary mouse keratinocyte cultures by TPA but not by RPA and inhibition of the clastogenic effects by ETYA and Antipain

R. T. Dzarlieva-Petrusevska, N. Fusenig
  • Cancer Lett., JO(Suppl.): S62,
  • 1986
VIEW 1 EXCERPT

Protein kinase C activation by diacylglycerol second messengers

R. M. Bell
  • Cell, 45:631-632,
  • 1986
VIEW 2 EXCERPTS

Protein kinase C activation by diacylglycerol second messengers

R. M. Bell
  • Cell, 45:631-632,
  • 1986
VIEW 2 EXCERPTS