Phloretin and phloretin analogs: Mode of action in planar lipid bilayers and monolayers

@article{Reyes2005PhloretinAP,
  title={Phloretin and phloretin analogs: Mode of action in planar lipid bilayers and monolayers},
  author={Juan Carlos Salcedo Reyes and Frank Anthony Greco and Ren{\'e} Motais and Ram{\'o}n Latorre},
  journal={The Journal of Membrane Biology},
  year={2005},
  volume={72},
  pages={93-103}
}
Phloretin and other neutral phloretin-like molecules are able to decrease the electrostatic potential within neutral lipid bilayers and monolayers. The relationship between the change in the dipole potential and the aqueous concentration of the molecule is well described by a Langmuir isotherm. From the Langmuir isotherm, the apparent dissociation constants (K D A ) and the maximum dipole potential change (ΔΔψ max) are obtained for the different phloretin-like molecules tested. Considering the… CONTINUE READING
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