Phloretin Prevents High-Fat Diet-Induced Obesity and Improves Metabolic Homeostasis

@article{Alsanea2017PhloretinPH,
  title={Phloretin Prevents High-Fat Diet-Induced Obesity and Improves Metabolic Homeostasis},
  author={Sary Alsanea and Mingming Gao and Dexi Liu},
  journal={The AAPS Journal},
  year={2017},
  volume={19},
  pages={797-805}
}
Reactive oxygen species generated as a by-product in metabolism play a central role in the development of obesity and obesity-related metabolic complications. The objective of the current study is to explore the possibility to block obesity and improve metabolic homeostasis via phloretin, a natural antioxidant product from apple tree leaves and Manchurian apricot. Both preventive and therapeutic activities of phloretin were assessed using a high-fat diet-induced obesity mouse model. Phloretin… CONTINUE READING

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