Phlefargesiine A, a C16N2 Lycopodium alkaloid with an unprecedented [6/7/6/6]-tetracyclic skeleton from Phlegmariurus fargesii

@article{Meng2016PhlefargesiineAA,
  title={Phlefargesiine A, a C16N2 Lycopodium alkaloid with an unprecedented [6/7/6/6]-tetracyclic skeleton from Phlegmariurus fargesii},
  author={Wei-Jia Meng and Juan Xiong and Wen-Xuan Wang and Hai-Yan Zhang and Huaqiang Zeng and Jin-Feng Hu},
  journal={Tetrahedron Letters},
  year={2016},
  volume={57},
  pages={3218-3221}
}
Abstract A novel C16N2 Lycopodium alkaloid, phlefargesiine A (1), was isolated from the whole plant of the club moss Phlegmariurus fargesii. The structure and absolute configuration were determined by extensive spectroscopic and computational methods. Compound 1 possesses an unprecedented [6/7/6/6]-tetracyclic framework, of which the seven-membered ring (ring B) is constructed through a hitherto unknown C-4–C-14 linkage. 
Phlefargesiine A, a C16N2 Lycopodium Alkaloid with an Unprecedented [6/7/6/6]-Tetracyclic Skeleton from Phlegmariurus fargesii.
The novel C16N2 Lycopodium alkaloid, phlefargesiine A (I), isolated from the whole plant of the club moss Phlegmariurus fargesii shows week inhibitory effect against acetylcholinesterase.
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