Philadelphia chromosome--positive pre-B-lymphocytic leukemia in a child.


A boy with acute lymphocytic leukemia (ALL) associated with a pre-B-cell phenotype and the Ph' chromosome is described. The Ph'-positive blasts with L3 morphology contained intracytoplasmic IgM but lacked surface immunoglobulins. The child's response to intensive chemotherapy was unsatisfactory. The short survival of our patient suggests that childhood… (More)


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