Phenytoin reduces suxamethonium-induced myalgia.

@article{Hatta1992PhenytoinRS,
  title={Phenytoin reduces suxamethonium-induced myalgia.},
  author={V Hatta and Abha Saxena and Heema Kaul},
  journal={Anaesthesia},
  year={1992},
  volume={47 8},
  pages={664-7}
}
A prospective, randomised trial was undertaken in 60 healthy adults to determine the efficacy of intravenously administered phenytoin in doses of 5 mg.kg-1 for the prevention of suxamethonium-induced fasciculations, a rise in serum K+ and myalgia. This was compared with tubocurarine pretreatment and no pretreatment (control group). Phenytoin pretreatment… CONTINUE READING