Phenytoin partially antagonized L-type Ca2+ current in glucagon-secreting tumor cells (ITC-1)


Transmembrane Ca2+ currents were investigated by means of a whole-cell clamp technique in a hamster glucagon-secreting tumor cell line (ITC-1). Two types of Ca2+ current were identified in ITC-1 cells. The low-threshold and transient (T-type) current became detectable above the potential level around −60 mV and decayed rapidly with an inactivation time… (More)
DOI: 10.1007/BF00175473


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