Phenytoin as a coanalgesic in cancer pain.

  title={Phenytoin as a coanalgesic in cancer pain.},
  author={Santosh V Yajnik and Gyanendra Pratap Singh and Mukesh Kumar},
  journal={Journal of pain and symptom management},
  volume={7 4},
The efficacy of phenytoin (PHT), buprenorphine (Bu), and Bu+PHT for the relief of cancer pain of various etiologies was evaluated in a randomized, double-blind study of 3 groups, each comprised of 25 patients. Treatment duration was 1 month. PHT (100 mg by mouth twice daily) provided greater than 50% pain relief to 18 patients (72%) and greater than 75… CONTINUE READING