Phenylpropanolamine contained in cold remedies and risk of hemorrhagic stroke

@article{Yoon2007PhenylpropanolamineCI,
  title={Phenylpropanolamine contained in cold remedies and risk of hemorrhagic stroke},
  author={Byung-Woo Yoon and H-J Bae and Keun-sik Hong and Sook Mee Lee and B J Park and Kyung-Ho Yu and M. K. Han and Y S Lee and D K. Chung and J. M. Park and S. W. Jeong and B. C. Lee and K. H. Cho and Jin Sug Kim and Seong Han Lee and K. M. Yoo},
  journal={Neurology},
  year={2007},
  volume={68},
  pages={146 - 149}
}
In this study, we sought to elucidate whether phenylpropanolamine (PPA) in cold remedies (small and divided doses) increases the risk of hemorrhagic stroke (HS). PPA exposure significantly increased the risk, and the risk was much higher in women. In women, linear trends were also found in recency, duration, and dosage of PPA exposure. PPA contained in cold remedies increases the risk of HS, particularly in women. 

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STROKE AND PHENYLPROPANOLAMINE USE