Phenylpropanoid and phenylisoprenoid metabolites from Asteraceae species as inhibitors of protein carbonylation.

@article{Marn2011PhenylpropanoidAP,
  title={Phenylpropanoid and phenylisoprenoid metabolites from Asteraceae species as inhibitors of protein carbonylation.},
  author={Marta Mar{\'i}n and Rosa Mar{\'i}a Giner and Mar{\'i}a del Carmen Recio and Salvador M{\'a}{\~n}ez},
  journal={Phytochemistry},
  year={2011},
  volume={72 14-15},
  pages={
          1821-5
        }
}
Three phenolic antioxidant and anti-inflammatory compounds: 7-methylaromadendrin, isoprenylhydroquinone glucoside, and 3.5-dicaffeoylquinic acid methyl ester, all isolated from Western Mediterranean Asteraceae species, have been studied for their inhibitory activity against protein carbonylation, a harmful post-translational modification of peptide chains associated with degenerative diseases. All compounds have proven to be effective, with 50% inhibitory concentration (IC₅₀) values in the… Expand
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