Phenylmethanesulfonyl fluoride delays the recovery from crush of peripheral nerves in hens.

@article{Moretto1993PhenylmethanesulfonylFD,
  title={Phenylmethanesulfonyl fluoride delays the recovery from crush of peripheral nerves in hens.},
  author={Angelo Moretto and Eugenio Capodicasa and Maja Peraica and Marcello Lotti},
  journal={Chemico-biological interactions},
  year={1993},
  volume={87 1-3},
  pages={457-62}
}
Several esterase inhibitors (carbamates, phosphinates and sulfonyl halides) have been shown to promote organophosphate-induced delayed polyneuropathy (OPIDP). The mechanism of promotion is not understood, but indirect evidence suggests impairments of peripheral nerve repair. Also, other toxic neuropathies, such as those caused by 2,5-hexanedione in hens and bromophenylacetylurea in rats, have been reported to be promoted by phenylmethanesulfonyl fluoride (PMSF). Hen sciatic nerve was crushed at… CONTINUE READING

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