Phenotyping of Lewis and secretor HBGA from saliva and detection of new FUT2 gene SNPs from young children from the Amazon presenting acute gastroenteritis and respiratory infection.

@article{Moraes2019PhenotypingOL,
  title={Phenotyping of Lewis and secretor HBGA from saliva and detection of new FUT2 gene SNPs from young children from the Amazon presenting acute gastroenteritis and respiratory infection.},
  author={Marcia Terezinha Baroni de Moraes and Alberto Ign{\'a}cio Olivares Olivares and Alexandre Madi Fialho and F{\'a}bio Correia Malta and S{\'e}rgio da Silva E Mouta Junior and Romanul de Souza Bispo and Alvaro Jorge Velloso and Gabriel Azevedo Alves Leit{\~a}o and Carina Pacheco Cantelli and Johan Nordgren and Lennart Svenson and Marize Pereira Miagostovich and Jos{\'e} Paulo Gagliardi Leite},
  journal={Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases},
  year={2019},
  volume={70},
  pages={
          61-66
        }
}
The Histo-blood group antigens (HBGA) are host genetic factors associated with susceptibility to rotavirus (RV) and human norovirus (HuNoV), the major etiological agents of viral acute gastroenteritis (AGE) worldwide. The FUT2 gene expressing the alpha-1, 2-L- fucosyltransferase enzyme is important for gut HBGA expression, and also provides a composition of the phenotypic profile achieved through mutations occurring in populations with different evolutionary histories; as such, it can be… CONTINUE READING