Phenotypic variation and FMRP levels in fragile X.

  title={Phenotypic variation and FMRP levels in fragile X.},
  author={Danuta Z Loesch and Richard M. Huggins and Randi J. Hagerman},
  journal={Mental retardation and developmental disabilities research reviews},
  volume={10 1},
Data on the relationships between cognitive and physical phenotypes, and a deficit of fragile X mental retardation 1 (FMR1) gene-specific protein product, FMRP, are presented and discussed in context with earlier findings. The previously unpublished results obtained, using standard procedures of regression and correlations, showed highly significant associations in males between FMRP levels and the Wechsler summary and subtest scores and in females between these levels and the full-scale… CONTINUE READING