Phenotypic variability of growing cellular populations.

  title={Phenotypic variability of growing cellular populations.},
  author={Ting Lu and Tongye Shen and Matthew R. Bennett and Peter G. Wolynes and Jeff Hasty},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  volume={104 48},
The dynamics and diversity of proliferating cellular populations are governed by the interplay between the growth and death rates among the various phenotypes within a colony. In addition, epigenetic multistability can cause cells to spontaneously switch from one phenotype to another. By examining a generalized form of the relative variance of populations… CONTINUE READING