Phenotypic profile of alternative activation marker CD163 is different in Alzheimer’s and Parkinson’s disease

@inproceedings{Pey2014PhenotypicPO,
  title={Phenotypic profile of alternative activation marker CD163 is different in Alzheimer’s and Parkinson’s disease},
  author={Peixuan Pey and Ronald K. B. Pearce and Michail E. Kalaitzakis and W. Sue T. Griffin and S M Gentleman},
  booktitle={Acta neuropathologica communications},
  year={2014}
}
BACKGROUND Microglial activation is a pathological feature common to both Alzheimer's and Parkinson's diseases (AD and PD). The classical activation involves release of pro-inflammatory cytokines and reactive oxygen species. This is necessary for maintenance of tissue homeostasis and host defense, but can cause bystander damage when the activation is sustained and uncontrolled. In recent years the heterogeneous nature of microglial activation states in neurodegenerative diseases has become… CONTINUE READING

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