Phenotypic plasticity in adult sympathetic neurons: changes in neuropeptide expression in organ culture.

@article{Zigmond1992PhenotypicPI,
  title={Phenotypic plasticity in adult sympathetic neurons: changes in neuropeptide expression in organ culture.},
  author={Richard E Zigmond and H Hyatt-Sachs and Corisande Baldwin and Xiao M Qu and Yunjuan Sun and T W McKeon and Rebecca C Schreiber and U Vaidyanathan},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1992},
  volume={89 4},
  pages={1507-11}
}
Vasoactive intestinal peptide (VIP)-like immunoreactivity is present at low levels in the superior cervical ganglion of the adult rat, where immunostained neural processes, but only an occasional immunostained cell body, are found. However, when ganglia are maintained for 24 or 48 hr in organ culture, their content of VIP-like immunoreactivity increases 6- or 31-fold, respectively. When examined at 24 hr, the increase in VIP-like immunoreactivity is totally blocked by an inhibitor of RNA or… CONTINUE READING

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