Phenotypic outcomes of imprinted gene models in mice: elucidation of pre- and postnatal functions of imprinted genes.

@article{Cleaton2014PhenotypicOO,
  title={Phenotypic outcomes of imprinted gene models in mice: elucidation of pre- and postnatal functions of imprinted genes.},
  author={Mary A M Cleaton and Carol A Edwards and Anne C Ferguson-Smith},
  journal={Annual review of genomics and human genetics},
  year={2014},
  volume={15},
  pages={93-126}
}
Genomic imprinting is an epigenetic process causing expression of a subset of genes in a parent-of-origin-specific manner. Among vertebrates, only therian mammals have been demonstrated to imprint, indicating that placentation and imprinting arose at similar time points in evolution and that imprinting may be involved in key mammal-specific processes. However, although several theories have been posited to explain the evolution of imprinting, each has shortcomings and none fully explains the… CONTINUE READING

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Mouse Genome Database Group

  • JA Blake, CJ Bult, JT Eppig, JA Kadin, JE Richardson
  • Nucleic Acids Res
  • 2014
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