Phenotypic modulation of porcine CD14+ monocytes, natural killer/natural killer T cells and CD8αβ+ T cell subsets by an antibody-derived killer peptide (KP).

Abstract

An engineered killer peptide (KP) based on a recombinant anti-idiotypic antibody representing the functional image of a yeast killer toxin (KT) was demonstrated to mediate antimicrobial effects against fungi and viruses. KP binds to murine dendritic cells and macrophages and up-regulate co-receptor expression, thus sustaining CD4+ lymphocyte activation. No… (More)
DOI: 10.1016/j.rvsc.2016.09.008

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Cite this paper

@article{Ferrari2016PhenotypicMO, title={Phenotypic modulation of porcine CD14+ monocytes, natural killer/natural killer T cells and CD8αβ+ T cell subsets by an antibody-derived killer peptide (KP).}, author={Luca S. Ferrari and Paolo Borghetti and Giulia Ferrarini and Elena de Angelis and Elena Canelli and Giulia Ogno and Alessia Catella and Tecla Ciociola and Walter Magliani and Paolo Martelli}, journal={Research in veterinary science}, year={2016}, volume={109}, pages={29-39} }