Phenotypic heterogeneity of persistent expansions of CD4+ CD8+ T cells.

A group of 18 individuals is described that manifest persistent (follow up between 4 and 57 months) expansions (ranging from 10 to 70%) of CD4+ CD8+ peripheral T cells. In nine individuals there was no apparent underlying disease whereas the remaining displayed a wide range of unrelated diseases. Analysis of the cell surface immunophenotype showed that all… CONTINUE READING