Phenotypic expression of B-lymphocytes. 2. Immunoglobulin expression of germinal center cells.


With a sensitive and specific immunohistochemical technique, immunoglobulin expression was examined in germinal centers with frozen and paraffin-embedded tissues. The majority of cells positive for surface immunoglobulin (IgM and IgD) were confined to the dark zone of the germinal center, while the cells positive for cytoplasmic immunoglobulin (IgM and IgG… (More)



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