Phenotypic diversity of Escherichia coli O157:H7 strains associated with the plasmid O157

@article{Lim2010PhenotypicDO,
  title={Phenotypic diversity of Escherichia coli O157:H7 strains associated with the plasmid O157},
  author={Ji Youn Lim and Joon Bae Hong and Haiqing Q Sheng and Smriti Shringi and Rajinder K. Kaul and Thomas E. Besser and Carolyn J. Hovde},
  journal={The Journal of Microbiology},
  year={2010},
  volume={48},
  pages={347-357}
}
Escherichia coli O157:H7, a food-borne pathogen, causes hemorrhagic colitis and the hemolytic-uremic syndrome. A putative virulence factor of E. coli O157:H7 is a 60-MDa plasmid (pO157) found in 99% of all clinical isolates and many bovine-derived strains. The well characterized E. coli O157:H7 Sakai strain (Sakai) and its pO157-cured derivative (Sakai-Cu) were compared for phenotypic differences. Sakai-Cu had enhanced survival in synthetic gastric fluid, did not colonize cattle as well as wild… CONTINUE READING

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