Phenotypic definition of effector and memory T-lymphocyte subsets in mice chronically infected with Mycobacterium tuberculosis.

@article{HenaoTamayo2010PhenotypicDO,
  title={Phenotypic definition of effector and memory T-lymphocyte subsets in mice chronically infected with Mycobacterium tuberculosis.},
  author={Marcela I. Henao-Tamayo and Diane J. Ordway and Scott M. Irwin and Shaobin Shang and Crystal A. Shanley and Ian M. Orme},
  journal={Clinical and vaccine immunology : CVI},
  year={2010},
  volume={17 4},
  pages={618-25}
}
The bacterium Mycobacterium tuberculosis remains one of the world's most successful pathogens, a situation that is aggravated by the fact that the existing vaccine, Mycobacterium bovis BCG, is not effective in adults. As with any vaccine, the purpose of giving BCG vaccination is to establish a long-lived state of memory immunity, but whether this is successfully completely established is still unclear. It is generally accepted that memory T cells can be divided into central and effector memory… CONTINUE READING
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