Phenotypic characterization of regulatory CD4+CD25+ T cells in rats.

@article{Stephens2004PhenotypicCO,
  title={Phenotypic characterization of regulatory CD4+CD25+ T cells in rats.},
  author={Leigh Andrea Stephens and A. Neil Barclay and Don W. Mason},
  journal={International immunology},
  year={2004},
  volume={16 2},
  pages={
          365-75
        }
}
CD25 has become widely used as a marker for a subset of regulatory CD4(+) T cells present in the thymus and periphery of mice, rats and humans. However, CD25 is also expressed on conventionally activated T cells that are not regulatory and not all peripheral regulatory T cells express CD25. The identification of a stable and unique marker for regulatory T cells would therefore be valuable. This study provides a detailed account of the phenotype of CD4(+)CD25(+) regulatory T cells in rats. In… 
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