Phenotypic characterization of normal and CML CD34-positive cells: only the most primitive CML progenitors include Ph-neg cells.

Abstract

We studied the sequence of acquisition of CD33, CD38 and HLA-DR antigens on CD34+ cells from marrow and blood of Ph-chromosome positive CML patients and normal marrow. We examined the Ph status of the various CML cell populations. The mean proportions of normal and CML CD34+ cells expressing CD33 and CD38 were not significantly different. However, a… (More)

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@article{Fabritiis1993PhenotypicCO, title={Phenotypic characterization of normal and CML CD34-positive cells: only the most primitive CML progenitors include Ph-neg cells.}, author={Paola De Fabritiis and Charles Dowding and J B Bungey and Alexander J. Chase and Graham Angus and Richard M. Szydlo and J. M. Goldman}, journal={Leukemia & lymphoma}, year={1993}, volume={11 1-2}, pages={51-61} }