Phenotypic characterization of immortalized normal and primary tumor-derived human prostate epithelial cell cultures.

@article{Schwab2000PhenotypicCO,
  title={Phenotypic characterization of immortalized normal and primary tumor-derived human prostate epithelial cell cultures.},
  author={Tracy S. Schwab and Timothy Stewart and Jutta Lehr and Kenneth J. Pienta and J. S. Rhim and Jill Macoska},
  journal={The Prostate},
  year={2000},
  volume={44 2},
  pages={164-71}
}
BACKGROUND Cell lines can provide powerful model systems for the study of human tumorigenesis. However, the human prostate cancer cell lines studied most intensively by investigators (PC3, DU145, and LNCaP) were established from metastatic lesions, and it is unlikely that they accurately recapitulate the genetic composition or biological behavior of primary prostate tumors. Cell lines more appropriate for the study of human prostate primary tumors would be those derived from spontaneously… CONTINUE READING
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Identification of a high frequency of chromosomal rearrangements in the centromeric regions of prostate cancer cell lines by sequential Giemsa-banding and spectral karyotyping

  • B Beheshti, J Karaskova, OC Park, J Squire, BG. Beatty
  • Mol Diagn
  • 2000

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