Phenotypic characteristics of hereditary non-polyposis colorectal cancer by the Amsterdam criteria: an Asian perspective.

@article{Chew2008PhenotypicCO,
  title={Phenotypic characteristics of hereditary non-polyposis colorectal cancer by the Amsterdam criteria: an Asian perspective.},
  author={Min-hoe Chew and P L Koh and K H Ng and J F Lim and Kok-Sun Ho and B L Ooi and C B Tang and Kong-weng Eu},
  journal={ANZ journal of surgery},
  year={2008},
  volume={78 7},
  pages={556-60}
}
BACKGROUND Hereditary non-polyposis colorectal cancer (HNPCC) is an autosomal disease with a 68-82% lifetime risk of colorectal cancer (CRC). This study examined the phenotypic characteristics of CRC in Amsterdam criteria-positive Asian patients from the Singapore Polyposis Registry. METHODS Hereditary non-polyposis CRC patients, defined by the Amsterdam I and II criteria, prospectively monitored in the Singapore Polyposis Registry over a 16-year period were reviewed. Clinical data were… CONTINUE READING

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