Phenotypic and transcriptomic characterization of Bacillus subtilis mutants with grossly altered membrane composition.

@article{Salzberg2008PhenotypicAT,
  title={Phenotypic and transcriptomic characterization of Bacillus subtilis mutants with grossly altered membrane composition.},
  author={Letal I Salzberg and John D. Helmann},
  journal={Journal of bacteriology},
  year={2008},
  volume={190 23},
  pages={7797-807}
}
The Bacillus subtilis membrane contains diacylglycerol-based lipids with at least five distinct headgroups that together help to define the physical and chemical properties of the lipid bilayer. Here, we describe the phenotypic characterization of mutant strains lacking one or more of the following lipids: glycolipids (ugtP mutants), phosphatidylethanolamine (pssA and psd mutants), lysylphosphatidylglycerol (mprF), and cardiolipin (ywnE and ywjE). Alterations of membrane lipid headgroup… CONTINUE READING
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