Phenotypic and genotypic assays for the detection and identification of adhesins from pyelonephritic Escherichia coli.


Four different gene clusters have been characterized so far which encode adhesins involved in the specific binding of pathogenic Escherichia coli to epithelial cells of the urinary tractus: the pap, sfa, afa and bma operons. The ability to adhere to uroepithelial cells and to interact with one or several of the specific receptors identified for each of the… (More)


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