Phenotypic and functional comparison of mesenchymal stem cells derived from the bone marrow of normal adults and patients with hematologic malignant diseases.

@article{Zhao2007PhenotypicAF,
  title={Phenotypic and functional comparison of mesenchymal stem cells derived from the bone marrow of normal adults and patients with hematologic malignant diseases.},
  author={Zhigang Zhao and Yan Liang and Kai Li and Wei-ming Li and Qiu-bai Li and Zhi-chao Chen and Ping Zou},
  journal={Stem cells and development},
  year={2007},
  volume={16 4},
  pages={637-48}
}
Mesenchymal stem cells (MSCs) have received much attention for their ability to differentiate into various cell types under specific conditions and to support the proliferation of hematopoietic stem cells. However, it is unclear whether the characteristics of MSCs are altered in different disease states. In this study, we obtained and expanded MSCs from bone marrow of patients with acute lymphoblastic leukemia (ALL), Hodgkin disease (HD), and non-Hodgkin lymphoma (NHL). Our results showed that… CONTINUE READING

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